Ketone supplementation decreases tumor cell viability and prolongs ...

Normal cells can use ketone bodies for energy, but cancer cell's can't. In mice with metastatic cancer, ketone supplementation prolonged survival by up to 69%. I don't care if it's just a mouse study. Had I metastatic cancer, I'd find a source for the ketone ester they used and take it.

Mice were fed a standard diet supplemented with either 1,3-butanediol (BD) or a ketone ester (KE), which are metabolized to the ketone bodies βHB and acetoacetate. Tumor growth was monitored by in vivo bioluminescent imaging. Survival time, tumor growth rate, blood glucose, blood βHB and body weight were measured throughout the survival study. Ketone supplementation decreased proliferation and viability of the VM-M3 cells grown in vitro, even in the presence of high glucose. Dietary ketone supplementation with BD and KE prolonged survival in VM-M3 mice with systemic metastatic cancer by 51 and 69%, respectively (p < 0.05). Ketone administration elicited anticancer effects in vitro and in vivo independent of glucose levels or calorie restriction. The use of supplemental ketone precursors as a cancer treatment should be further investigated in animal models to determine potential for future clinical use. [emphasis mine]

Tags: ketone ester supplements, metastatic cancer

Views: 88

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There will come a day when I shall be a willing human volunteer for any trial.

My cancer is metastatic, although currently suppressed by androgen blockade (by chemotherapy and 3-monthly injections). 

Ouch! One product easily available is KetoForce by Prototype Nutrition.

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