Obesity is associated with numerous problems and is increasing in prevalence throughout developed nations.

From a thermodynamical viewpoint, weightloss is easy: burn more energy than you consume. In practice, weightloss can be confounded by improper diet, some drugs, and unappealing exercise.

In this thread, we will discuss research related to weightloss and how to apply it to your own life.

As always, nothing in this thread constitutes medical advice; always discuss your weightloss plan with your medical doctor.

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Dietary sugars stimulate fatty acid synthesis in adults.

Long article short: high fructose corn syrup is bad for you.

Not only does it appear that HFCS gets preferentially converted to triglycerides (fat), but it appears that HFCS will cause fat consumed in later meals to be stored by the body.

Also, consumption of fructose, glucose, or sucrose will make you hungrier.

There is no scientific consensus on the effects of HFCS, but the evidence does link it to obesity. If you are trying to lose weight, it would be a good idea to severely curtail your sugar consumption in general. If you are just trying to stay healthy, you should consider avoiding HFCS.
Don't skip breakfast!

Breakfast plays (a meal eaten within two hours of waking) does two things for you: It increases your energy throughout the day, so you burn more energy, and it decreases appetite and energy intake. [File 1]

Eating breakfast, especially fruits, whole grains, and fiber is correlated with a lower BMI and a reduced risk of chronic diseases. [File 2]
Drop those artificial sweeteners!

Recent research has shown mixed results in the use of artificial sweeteners for weight control. It has been hypothesized that the use of artificial sweeteners "short-circuits" the brain's identification of sweet and calorie consumption. [Intense sweeteners and body weight]

Two studies support this hypothesis:

The first, in rats, shows that rats who are fed saccharin consume more calories and gain more weight, a paradoxical outcome.[Calories and energy regulation in rats]

The second study, using fMRI in humans, shows that artificial sweeteners activate regions of the brain differently than sugar. Notably, artificial sweetener does not activate the dopaminergic midbrain area: eating sugar makes you happy, whereas artificial sweetener does not. [Human taste pathways and sweetener]




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